Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease
نویسندگان
چکیده
منابع مشابه
Mild cognitive impairment represents early-stage Alzheimer disease.
BACKGROUND Mild cognitive impairment (MCI) is considered to be a transitional stage between aging and Alzheimer disease (AD). OBJECTIVE To determine whether MCI represents early-stage AD by examining its natural history and neuropathologic basis. DESIGN A prospective clinical and psychometric study of community-living elderly volunteers, both nondemented and minimally cognitively impaired, ...
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The growth in ageing population in recent years has resulted in increasing prevalence of dementia. Alzheimer Disease (AD) is the most common cause of dementia [1] particularly, among the aged population. The most accurate way to diagnose AD is to analyze histopathological changes showing amyloid plaques and neurofibrillary bundles. However, in practice, the diagnosis is often based on clinical ...
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AIM The aim of this study was to identify mild cognitive deficits in Parkinson's disease (PD) prior to extensive neurodegeneration and to evaluate the extent to which dopamine depletion and other disease-related predictors can explain cognitive profiles. METHODS Neuropsychological performances of 40 nondemented early-stage PD patients and 42 healthy controls were compared across on or off dop...
متن کاملCognitive decline in prodromal Alzheimer disease and mild cognitive impairment.
OBJECTIVE To characterize the course of cognitive decline during the prodromal phase of Alzheimer disease. DESIGN Longitudinal cohort study with up to 16 years of observation. PARTICIPANTS Older persons from 2 studies underwent annual clinical evaluations that included cognitive function testing and clinical classification of mild cognitive impairment, dementia, and Alzheimer disease. At ba...
متن کاملEffect of Mild Cognitive Impairment and Alzheimer Disease on Auditory Steady-State Responses
Introduction: Mild Cognitive Impairment (MCI), a disorder of the elderly people, is difficult to diagnose and often progresses to Alzheimer Disease (AD). Temporal region is one of the initial areas, which gets impaired in the early stage of AD. Therefore, auditory cortical evoked potential could be a valuable neuromarker for detecting MCI and AD. Methods: In this study, the thresholds of...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2001
ISSN: 0003-9942
DOI: 10.1001/archneur.58.3.397